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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MYBL2 All Species: 28.79
Human Site: S577 Identified Species: 48.72
UniProt: P10244 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P10244 NP_002457.1 700 78764 S577 R K P G L R R S P I K K V R K
Chimpanzee Pan troglodytes XP_514658 769 86303 S577 R K P G L R R S P I K K V R K
Rhesus Macaque Macaca mulatta XP_001084853 700 78675 S577 R K P G L R R S P I K K V R K
Dog Lupus familis XP_534424 883 97262 S760 R K A G L R R S P I K K V R K
Cat Felis silvestris
Mouse Mus musculus P48972 704 79084 S581 R K P G L R R S P I K K V R K
Rat Rattus norvegicus NP_001100006 704 79549 S581 R K P G L R R S P I K K V R K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511778 753 85883 S619 S C K Q E Q V S S G K K V R K
Chicken Gallus gallus Q03237 686 77718 S560 R K Q G L R R S P I K K V R K
Frog Xenopus laevis P52551 743 82891 A605 Q V K T S K G A V V Q L G N T
Zebra Danio Brachydanio rerio NP_001003867 633 70853 E523 L D V I D C S E S V A A R K Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_797351 686 76826 D572 E K E N L T G D E T R Q E E A
Poplar Tree Populus trichocarpa
Maize Zea mays P20024 340 36221 I230 V I D I E P E I W S I I D G E
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9S7G7 776 86488 K649 G A P S I L K K R H R D L L S
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa O13493 324 36522 G214 H A F P T T D G Y Q D G S D G
Conservation
Percent
Protein Identity: 100 88 98.2 72.5 N.A. 85.2 87.7 N.A. 38.3 72.5 54.2 52.1 N.A. N.A. N.A. N.A. 37.8
Protein Similarity: 100 89.7 98.7 74.7 N.A. 89.4 91.3 N.A. 54.5 81.5 69 65.8 N.A. N.A. N.A. N.A. 54
P-Site Identity: 100 100 100 93.3 N.A. 100 100 N.A. 40 93.3 0 0 N.A. N.A. N.A. N.A. 13.3
P-Site Similarity: 100 100 100 93.3 N.A. 100 100 N.A. 46.6 93.3 33.3 20 N.A. N.A. N.A. N.A. 26.6
Percent
Protein Identity: N.A. 20.1 N.A. 25.5 N.A. 20.7
Protein Similarity: N.A. 31.8 N.A. 40.8 N.A. 29.5
P-Site Identity: N.A. 0 N.A. 6.6 N.A. 0
P-Site Similarity: N.A. 6.6 N.A. 33.3 N.A. 0
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 15 8 0 0 0 0 8 0 0 8 8 0 0 8 % A
% Cys: 0 8 0 0 0 8 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 8 8 0 8 0 8 8 0 0 8 8 8 8 0 % D
% Glu: 8 0 8 0 15 0 8 8 8 0 0 0 8 8 8 % E
% Phe: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 8 0 0 50 0 0 15 8 0 8 0 8 8 8 8 % G
% His: 8 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % H
% Ile: 0 8 0 15 8 0 0 8 0 50 8 8 0 0 0 % I
% Lys: 0 58 15 0 0 8 8 8 0 0 58 58 0 8 58 % K
% Leu: 8 0 0 0 58 8 0 0 0 0 0 8 8 8 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 8 0 0 0 0 0 0 0 0 0 8 0 % N
% Pro: 0 0 43 8 0 8 0 0 50 0 0 0 0 0 0 % P
% Gln: 8 0 8 8 0 8 0 0 0 8 8 8 0 0 8 % Q
% Arg: 50 0 0 0 0 50 50 0 8 0 15 0 8 58 0 % R
% Ser: 8 0 0 8 8 0 8 58 15 8 0 0 8 0 8 % S
% Thr: 0 0 0 8 8 15 0 0 0 8 0 0 0 0 8 % T
% Val: 8 8 8 0 0 0 8 0 8 15 0 0 58 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _